What if your virtual classroom experiences were so effective, people clamored to attend? If you've ever had a hunch that certain digital learning experiences work better than others, there is probably a solid neurological principle to back that up. Explore six brain-based principles that result in maximum learning retention, transfer, and application in the virtual classroom. Move people through collaborating, thinking, doing, giving feedback, and receiving feedback, as they build new synapses that support long-term retention and application of critical concepts. Change the way you design and deliver virtual learning experiences as you leverage the neuroscience of learning to ensure on-the-job behavior change and application of new skills. This session was recorded at the ATD 2019 TechKnowledge conference in West Palm Beach, Florida.